top of page
Worldwide, osteoporosis causes more than 8.9 million fractures annually
1st Generic Teriparatide in the world backed by clinical trial
For patients who are suffering from fragility fractures due to osteoporosis
​
Rebuild your bones..Restore your strength.. Regains quality of life
Description:
-
Osteotide is a sterile solution for injection containing Teriparatide (recombinant human parathyroid hormone 1-34).
-
It is produced by using a strain of E. coli employing recombinant DNA technology.
-
Its sequence is identical to that of 34-N terminal amino acids (the biologically active region) of the endogenous 84-amino acid human parathyroid hormone.
-
It is a water soluble protein with a molecular weight of 4117.8 Daltons.
​
Parathyroid hormone:
-
Parathyroid hormone (PTH) is hormone secreted by the Parathyroid gland.
-
PTH is secreted in response to low blood serum calcium levels.
-
It regulates serum calcium level through its effect on bones, kidneys and intestines.
-
PTH influences bone the remodeling, in which the bone tissue is resorbed and rebuilt alternatively.
-
There are two types of cells in bones
-
Osteoclast: are the cells that break down bone tissue.
-
Osteoblast: are the cells that form new bone tissue.
-
-
The PTH indirectly stimulates the osteoclast activity within the bone matrix (osteon) in an effort to release more ionic calcium (Ca2+) into the blood to elevate a low serum calcium level.
-
The bones act as a "storage house" from which the body can make the"withdrawals" as needed to keep the amount of calcium in the blood (serum calcium) at appropriate levels.
-
PTH is secreted primarily by the chief cells of the parathyroid glands.
​
​
​
​
​
​
​
​
​
​
​
​
​
​
​
​
​
​
​
bottom of page